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Salmonella typhimurium Infection in Mice Induces Nitric Oxide-Mediated Immunosuppression through a Natural Killer Cell-Dependent Pathway

Splenocytes isolated from C57BL/6J female mice 3 to 7 days after inoculation with an attenuated strain of Salmonella typhimurium produced high levels of nitric oxide (39 to 77 μM) and gamma interferon (IFN-γ). Additionally, spleen cell cultures from Salmonella-inoculated mice were markedly suppresse...

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Detalhes bibliográficos
Main Authors: Schwacha, Martin G., Meissler, Joseph J., Eisenstein, Toby K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108742/
https://ncbi.nlm.nih.gov/pubmed/9826366
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