Genomic Subtraction Followed by Dot Blot Screening of Streptococcus pneumoniae Clinical and Carriage Isolates Identifies Genetic Differences Associated with Strains That Cause Otitis Media

Streptococcus pneumoniae strains are the leading cause of bacterial otitis media, yet little is known about specific bacterial factors important for this disease. We utilized a molecular epidemiological approach involving genomic subtraction of the S. pneumoniae serogroup 19 middle ear strain 5093 a...

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Detalhes bibliográficos
Main Authors: Pettigrew, Melinda M., Fennie, Kristopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087362/
https://ncbi.nlm.nih.gov/pubmed/15845484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.2805-2811.2005
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