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Myosin-1a Is Critical for Normal Brush Border Structure and Composition

To develop our understanding of myosin-1a function in vivo, we have created a mouse line null for the myosin-1a gene. Myosin-1a knockout mice demonstrate no overt phenotypes at the whole animal level but exhibit significant perturbations and signs of stress at the cellular level. Among these are def...

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Autori principali: Tyska, Matthew J., Mackey, Andrew T., Huang, Jian-Dong, Copeland, Neil G., Jenkins, Nancy A., Mooseker, Mark S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087248/
https://ncbi.nlm.nih.gov/pubmed/15758024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1116
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