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Effect of P39 Gene Deletion in Live Brucella Vaccine Strains on Residual Virulence and Protective Activity in Mice

The 39-kilodalton protein (P39) has previously been shown to be an immunodominant protein in Brucella infections. P39 gene deletion mutants of vaccine strains Brucella abortus S19 and Brucella melitensis Rev.1 were constructed by gene replacement. This deletion did not significantly modify the resid...

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Detalhes bibliográficos
Main Authors: Tibor, Anne, Jacques, Isabelle, Guilloteau, Laurence, Verger, Jean-Michel, Grayon, Maggy, Wansard, Valerie, Letesson, Jean-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108700/
https://ncbi.nlm.nih.gov/pubmed/9784574
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