Altered Expression of Selectable Marker URA3 in Gene-Disrupted Candida albicans Strains Complicates Interpretation of Virulence Studies

The ura-blaster technique for the disruption of Candida albicans genes has been employed in a number of studies to identify possible genes encoding virulence factors of this fungal pathogen. In this study, the URA3-encoded orotidine 5′-monophosphate (OMP) decarboxylase enzyme activities of C. albica...

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Main Authors: Lay, Jennifer, Henry, L. Keith, Clifford, Julie, Koltin, Yigal, Bulawa, Christine E., Becker, Jeffrey M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC108662/
https://ncbi.nlm.nih.gov/pubmed/9784536
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