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Neisseria gonorrhoeae Heme Biosynthetic Mutants Utilize Heme and Hemoglobin as a Heme Source but Fail To Grow within Epithelial Cells

Many bacterial pathogens, including pathogenic neisseriae, can use heme as an iron source for growth. To study heme utilization by Neisseria gonorrhoeae, two heme biosynthetic mutants were constructed, one with a mutation in hemH (the gene encoding ferrochelatase) and one with a mutation in hemA (th...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Turner, Paul C., Thomas, Christopher E., Elkins, Christopher, Clary, Susan, Sparling, P. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.11.5215-5223.1998
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