Mutational Analysis of Superantigen Activity Responsible for the Induction of Skin Erythema by Streptococcal Pyrogenic Exotoxin C

Streptococcal pyrogenic exotoxin C (SPEC), when injected intradermally, induces erythema in unsensitized rabbits. In the present study, we examined whether this erythema induction is due to the T-cell stimulatory activity of SPEC as a superantigen. Analysis by using single-residue mutant SPECs indic...

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Pubblicato in:	Infect Immun
Autori principali:	Yamaoka, Junichi, Nakamura, Eijiro, Takeda, Yoshifumi, Imamura, Sadao, Minato, Nagahiro
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9746612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.10.5020-5026.1998
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