Comparison of the PspA Sequence from Streptococcus pneumoniae EF5668 to the Previously Identified PspA Sequence from Strain Rx1 and Ability of PspA from EF5668 To Elicit Protection against Pneumococci of Different Capsular Types

PspA (pneumococcal surface protein A) is a serologically varied virulence factor of Streptococcus pneumoniae. In mice, PspA has been shown to elicit an antibody response that protects against fatal challenge with encapsulated S. pneumoniae, and the protection-eliciting residues have been mapped to t...

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Bibliografske podrobnosti

izdano v:	Infect Immun
Principais autores:	McDaniel, Larry S., McDaniel, D. Olga, Hollingshead, Susan K., Briles, David E.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Microbial Immunity and Vaccines
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9746574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.10.4748-4754.1998
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