Construction of a Stable Attenuated Shigella sonnei ΔvirG Vaccine Strain, WRSS1, and Protective Efficacy and Immunogenicity in the Guinea Pig Keratoconjunctivitis Model

Construction of a stable Shigella sonnei vaccine has been complicated by the instability of the virulence phenotype caused by the spontaneous loss of the invasion plasmid. To select a suitable candidate for vaccine construction, 16 S. sonnei strains were screened for stability of the virulence pheno...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hartman, Antoinette B., Venkatesan, Malabi M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 1998
נושאים:
Microbial Immunity and Vaccines
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC108562/
https://ncbi.nlm.nih.gov/pubmed/9712824
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