Role of CR4 in Mycobacterium tuberculosis-Human Macrophages Binding and Signal Transduction in the Absence of Serum

The β2 integrin CR4 is involved in Mycobacterium tuberculosis phagocytosis by human mononuclear phagocytes through the opsonin C3bi. In this study, we demonstrate that M. tuberculosis can bind directly to monocyte-derived macrophages via CR4 in the absence of any opsonins. CR4-transfected CHO cells...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Zaffran, Yona, Zhang, Li, Ellner, Jerrold J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4541-4544.1998
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