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Deletion of the Central Proline-Rich Repeat Domain Results in Altered Antigenicity and Lack of Surface Expression of the Streptococcus mutans P1 Adhesin Molecule

Members of the family of surface adhesins of oral streptococci, including P1 of Streptococcus mutans, contain two highly conserved repeat domains, one rich in alanine (A region) and the other rich in proline (P region). To assess the contribution of the P region to the biological properties of P1, a...

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Udgivet i:Infect Immun
Principais autores: Brady, L. J., Cvitkovitch, D. G., Geric, C. M., Addison, M. N., Joyce, J. C., Crowley, P. J., Bleiweis, A. S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4274-4282.1998
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