Hemolytically Active (Acylated) Alpha-Hemolysin Elicits Interleukin-1β (IL-1β) but Augments the Lethality of Escherichia coli by an IL-1- and Tumor Necrosis Factor-Independent Mechanism

Many pathogenic Escherichia coli produce the toxin alpha-hemolysin (Hly), and lipopolysaccharide (LPS), interleukin-1 (IL-1), and tumor necrosis factor (TNF) have all been recognized as important effector molecules during infections by gram-negative organisms. Despite the characterization of many in...

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Опубликовано в::	Infect Immun
Главные авторы:	Gleason, Thomas G., Houlgrave, C. Webster, May, Addison K., Crabtree, Traves D., Sawyer, Robert G., Denham, Woody, Norman, James G., Pruett, Timothy L.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1998
Предметы:	Host Response and Inflammation
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4215-4221.1998
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