Low Endotoxic Potential of Legionella pneumophila Lipopolysaccharide due to Failure of Interaction with the Monocyte Lipopolysaccharide Receptor CD14

Legionella pneumophila, a gram-negative bacterium causing Legionnaires’ disease and Pontiac fever, was shown to be highly reactive in in vitro gelation of Limulus lysate but not able to induce fever and the local Shwartzman reaction in rabbits and mice. We analyzed the capacity of purified L. pneumo...

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Bibliographic Details
Main Authors: Neumeister, B., Faigle, M., Sommer, M., Zähringer, U., Stelter, F., Menzel, R., Schütt, C., Northoff, H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108499/
https://ncbi.nlm.nih.gov/pubmed/9712761
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