Production and Characterization of a Set of Mouse-Human Chimeric Immunoglobulin G (IgG) Subclass and IgA Monoclonal Antibodies with Identical Variable Regions Specific for Pseudomonas aeruginosa Serogroup O6 Lipopolysaccharide

The heavy- and light-chain variable regions from a murine monoclonal antibody that recognize Pseudomonas aeruginosa serogroup O6 lipopolysaccharide (LPS) were used to generate a series of chimeric mouse-human monoclonal antibodies with identical variable regions. The murine variable-region gene segm...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Preston, Michael J., Gerçeker, A. Alev, Reff, Mitchell E., Pier, Gerald B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4137-4142.1998
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