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Transgenic Expression of a Mosquito-Stage Malarial Protein, Pbs21, in Blood Stages of Transformed Plasmodium berghei and Induction of an Immune Response upon Infection

Pbs21 is a surface protein of the ookinete of Plasmodium berghei, which can induce a potent transmission-blocking immune response. Pbs21 is normally expressed only by parasite stages in the mosquito, i.e., female gametes/zygotes, ookinetes, and oocysts. However, the Pbs21 gene is transcribed in fema...

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Detalhes bibliográficos
Main Authors: Margos, Gabriele, van Dijk, Melissa R., Ramesar, Jai, Janse, Chris J., Waters, Andrew P., Sinden, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108443/
https://ncbi.nlm.nih.gov/pubmed/9673276
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