Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability
The cAMP-dependent signaling pathway has been implicated in cardiac cell growth/differentiation and muscle gene transcription. Previously, we have identified a cAMP-inducible E-box/M-CAT hybrid motif in the cardiac α-myosin heavy chain (α-MHC) gene promoter. The two factors, TEF-1 and Max, that bind...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10931933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.16.3168 |
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