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Valine 738 and lysine 735 in the fifth transmembrane domain of rTas1r3 mediate insensitivity towards lactisole of the rat sweet taste receptor

BACKGROUND: The sweet taste inhibitor lactisole acts on the human sweet taste receptor heteromer TAS1R2-TAS1R3 but not on its rodent counterpart. Recently, it was shown that the lactisole sensitivity of the human sweet taste receptor involves the part of TAS1R3 encompassing the seven transmembrane r...

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Détails bibliographiques
Auteurs principaux: Winnig, Marcel, Bufe, Bernd, Meyerhof, Wolfgang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084349/
https://ncbi.nlm.nih.gov/pubmed/15817126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-6-22
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