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Spontaneous muscle action potentials fail to develop without fetal-type acetylcholine receptors

In mammals, two combinations of muscle nicotinic acetylcholine receptors (AChRs) are used: α(2)βγδ (γ-AChR) or α(2)βɛδ (ɛ-AChR). After birth, γ-AChRs are replaced by ɛ-AChRs (γ/ɛ-switch). The two receptors have different conductances and open times. During perinatal period, the long open time γ-AChR...

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Detalhes bibliográficos
Main Authors: Takahashi, Masazumi, Kubo, Tai, Mizoguchi, Akira, Carlson, C. George, Endo, Katsuaki, Ohnishi, Katsunori
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084182/
https://ncbi.nlm.nih.gov/pubmed/12101101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf128
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