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Position-effect variegation in Drosophila: the modifier Su(var)3-7 is a modular DNA-binding protein

An increase in the dose of the Su(var)3-7 locus of Drosophila augments heterochromatin-promoted variegated silencing. The deduced protein sequence of Su(var)3-7 reveals seven widely spaced zinc fingers. We found that Su(var)3-7 has affinity for DNA in vitro and that the minimal protein sequence requ...

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Detalhes bibliográficos
Main Authors: Cléard, Fabienne, Spierer, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084161/
https://ncbi.nlm.nih.gov/pubmed/11743022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve243
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