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Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase

Novel ribozymes that couple the cleavage activity of hammerhead ribozymes with the unwinding activity of RNA helicase eIF4AI were constructed. This leads to extremely efficient cleavage of the target mRNA, regardless of the secondary structure of the RNA, and eliminates one of the major problems: ma...

詳細記述

保存先:
書誌詳細
主要な著者: Kawasaki, Hiroaki, Taira, Kazunari
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084111/
https://ncbi.nlm.nih.gov/pubmed/11964387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf098
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