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Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase
Tumor necrosis factor (TNF) ligand family members are synthesized as transmembrane proteins, and cleavage of the membrane-anchored proteins from the cell surface is frequently observed. The TNF-related ligands APRIL and BLyS and their cognate receptors BCMA/TACI form a two ligand/two receptor system...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084076/ https://ncbi.nlm.nih.gov/pubmed/11571266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve198 |
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