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Genetic manipulation of insulin signaling, action and secretion in mice: Insights into glucose homeostasis and pathogenesis of type 2 diabetes
Non-insulin-dependent diabetes mellitus (NIDDM) is a complex heterogeneous polygenic disease characterized mainly by insulin resistance and pancreatic β-cell dysfunction. In recent years, several genetically engineered mouse models have been developed for the study of the pathophysiological conseque...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084066/ https://ncbi.nlm.nih.gov/pubmed/11943762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf078 |
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