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Cavities and packing defects in the structural dynamics of myoglobin

Small globular proteins contain internal cavities and packing defects that reduce thermodynamic stability but seem to play a role in controlling function by defining pathways for the diffusion of the ligand/substrate to the active site. In the case of myoglobin (Mb), a prototype for structure–functi...

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Detalhes bibliográficos
Main Authors: Brunori, Maurizio, Gibson, Quentin H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083996/
https://ncbi.nlm.nih.gov/pubmed/11493595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve159
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