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CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri

Epithelial cells are refractory to extracellular lipopolysaccharide (LPS), yet when presented inside the cell, it is capable of initiating an inflammatory response. Using invasive Shigella flexneri to deliver LPS into the cytosol, we examined how this factor, once intracellular, activates both NF-κB...

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Détails bibliographiques
Auteurs principaux: Girardin, Stephen E., Tournebize, Régis, Mavris, Maria, Page, Anne-Laure, Li, Xiaoxia, Stark, George R., Bertin, John, DiStefano, Peter S., Yaniv, Moshe, Sansonetti, Philippe J., Philpott, Dana J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083992/
https://ncbi.nlm.nih.gov/pubmed/11463746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve155
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