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Angiostatin effects on endothelial cells mediated by ceramide and RhoA

Angiostatin is a cleavage product of plasminogen that has anti-angiogenic properties. We investigated whether the effects of angiostatin on endothelial cells are mediated by ceramide, a lipid implicated in endothelial cell signaling. Our results demonstrate that angiostatin produces a transient incr...

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Библиографические подробности
Главные авторы: Gupta, Nalin, Nodzenski, Edwardine, Khodarev, Nikolai N., Yu, Jianqing, Khorasani, Leila, Beckett, Michael A., Kufe, Donald W., Weichselbaum, Ralph R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083909/
https://ncbi.nlm.nih.gov/pubmed/11415988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve115
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