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Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans
Cyclophilin A is the target of the immunosuppressant cyclosporin A (CsA) and is encoded by a single unique gene conserved from yeast to humans. In the pathogenic fungus Cryptococcus neoformans, two homologous linked genes, CPA1 and CPA2, were found to encode two conserved cyclophilin A proteins. In...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Oxford University Press
2001
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083903/ https://ncbi.nlm.nih.gov/pubmed/11415984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve109 |
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