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Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function

Disruption of the signaling pathways mediated by the receptor tyrosine kinase Tek/Tie2 has shown that this receptor plays a pivotal role in vascularization of the developing embryo. In this report, we have utilized the tetracycline-responsive binary transgenic system to overcome the early lethal car...

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Hlavní autoři: Jones, Nina, Voskas, Daniel, Master, Zubin, Sarao, Renu, Jones, Jamie, Dumont, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083887/
https://ncbi.nlm.nih.gov/pubmed/11375937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve093
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