Pulmonary and Hepatic Gene Expression following Cecal Ligation and Puncture: Monophosphoryl Lipid A Prophylaxis Attenuates Sepsis-Induced Cytokine and Chemokine Expression and Neutrophil Infiltration

Polymicrobial sepsis induced by cecal ligation and puncture (CLP) reproduces many of the pathophysiologic features of septic shock. In this study, we demonstrate that mRNA for a broad range of pro- and anti-inflammatory cytokine and chemokine genes are temporally regulated after CLP in the lung and...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Salkowski, Cindy A., Detore, Gregory, Franks, Alice, Falk, Michael C., Vogel, Stefanie N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3569-3578.1998
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