Pulmonary and Hepatic Gene Expression following Cecal Ligation and Puncture: Monophosphoryl Lipid A Prophylaxis Attenuates Sepsis-Induced Cytokine and Chemokine Expression and Neutrophil Infiltration

Polymicrobial sepsis induced by cecal ligation and puncture (CLP) reproduces many of the pathophysiologic features of septic shock. In this study, we demonstrate that mRNA for a broad range of pro- and anti-inflammatory cytokine and chemokine genes are temporally regulated after CLP in the lung and...

Full description

Saved in:
Bibliographic Details
Main Authors: Salkowski, Cindy A., Detore, Gregory, Franks, Alice, Falk, Michael C., Vogel, Stefanie N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108388/
https://ncbi.nlm.nih.gov/pubmed/9673235
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items