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The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation

In chromosomal rearrangements of acute myeloid leukaemia patients the mixed lineage leukaemia (MLL) gene, a human homolog of the Drosophila gene trithorax, is frequently fused to AF10. Here we describe the identification and a functional characterization of the Drosophila homolog dAF10. We show that...

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Detalhes bibliográficos
Main Authors: Linder, Britta, Gerlach, Nina, Jäckle, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083836/
https://ncbi.nlm.nih.gov/pubmed/11266362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve039
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