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Chromosomal DNA demethylation specified by protein binding
In the present study, we utilize the well-characterized Escherichia coli lac repressor/operator system to demonstrate that protein binding can lead to demethylation at the binding sites in the chromosome. Similar to the findings using the episome, we found that the presence of LacI in the cells can...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083819/ https://ncbi.nlm.nih.gov/pubmed/11258701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve023 |
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