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Genome-wide insertional mutagenesis in human cells by the Drosophila mobile element Minos
The development of efficient non-viral methodologies for genome-wide insertional mutagenesis and gene tagging in mammalian cells is highly desirable for functional genomic analysis. Here we describe transposon mediated mutagenesis (TRAMM), using naked DNA vectors based on the Drosophila hydei transp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083762/ https://ncbi.nlm.nih.gov/pubmed/11258481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd089 |
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