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Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice
To dissect the effects of corticosteroids mediated by the mineralocorticoid (MR) and the glucocorticoid receptor (GR) in the central nervous system, we compared MR(–/–) mice, whose salt loss syndrome was corrected by exogenous NaCl administration, with GR(–/–) mice having a brain-specific disruption...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083761/ https://ncbi.nlm.nih.gov/pubmed/11258486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd088 |
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