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Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice

To dissect the effects of corticosteroids mediated by the mineralocorticoid (MR) and the glucocorticoid receptor (GR) in the central nervous system, we compared MR(–/–) mice, whose salt loss syndrome was corrected by exogenous NaCl administration, with GR(–/–) mice having a brain-specific disruption...

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Detalhes bibliográficos
Main Authors: Gass, Peter, Kretz, Oliver, Wolfer, David P., Berger, Stefan, Tronche, Francois, Reichardt, Holger M., Kellendonk, Christoph, Lipp, Hans-Peter, Schmid, Wolfgang, Schütz, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083761/
https://ncbi.nlm.nih.gov/pubmed/11258486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd088
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