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Activation of the Drosophila NF-κB factor Relish by rapid endoproteolytic cleavage

The Rel/NF-κB transcription factor Relish plays a key role in the humoral immune response in Drosophila. We now find that activation of this innate immune response is preceded by rapid proteolytic cleavage of Relish into two parts. An N-terminal fragment, containing the DNA-binding Rel homology doma...

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Bibliografiske detaljer
Main Authors: Stöven, Svenja, Ando, Istvan, Kadalayil, Latha, Engström, Ylva, Hultmark, Dan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083746/
https://ncbi.nlm.nih.gov/pubmed/11269501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd072
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