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Activation of the Drosophila NF-κB factor Relish by rapid endoproteolytic cleavage

The Rel/NF-κB transcription factor Relish plays a key role in the humoral immune response in Drosophila. We now find that activation of this innate immune response is preceded by rapid proteolytic cleavage of Relish into two parts. An N-terminal fragment, containing the DNA-binding Rel homology doma...

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Autors principals: Stöven, Svenja, Ando, Istvan, Kadalayil, Latha, Engström, Ylva, Hultmark, Dan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083746/
https://ncbi.nlm.nih.gov/pubmed/11269501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd072
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