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Activation of the Drosophila NF-κB factor Relish by rapid endoproteolytic cleavage
The Rel/NF-κB transcription factor Relish plays a key role in the humoral immune response in Drosophila. We now find that activation of this innate immune response is preceded by rapid proteolytic cleavage of Relish into two parts. An N-terminal fragment, containing the DNA-binding Rel homology doma...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083746/ https://ncbi.nlm.nih.gov/pubmed/11269501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd072 |
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