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Inactivation of MAP kinase signalling in Myc Transformed Cells and Rescue by LiCl inhibition of GSK3

c-Myc oncogene is an important regulator of cell cycle and apoptosis, and its dysregulated expression is associated with many malignancies. Myc is instrumental in directly or indirectly regulating the progression through the G1 phase and G1/S transition, and transformation by Myc results in perturbe...

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Autors principals: Al-Assar, Osama, Crouch, Dorothy H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083420/
https://ncbi.nlm.nih.gov/pubmed/15811177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-4-13
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