Phase 1 Evaluation of Vibrio cholerae O1, Serotype Inaba, Polysaccharide-Cholera Toxin Conjugates in Adult Volunteers

Conjugate vaccines were prepared by binding hydrazine-treated lipopolysaccharide (DeALPS) from Vibrio cholerae O1, serotype Inaba, to cholera toxin (CT) variants CT-1 and CT-2. Volunteers (n = 75) were injected with either 25 μg of DeALPS, alone or as a conjugate, or the licensed cellular vaccine co...

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Bibliografiske detaljer
Main Authors: Gupta, Rajesh K., Taylor, David N., Bryla, Dolores A., Robbins, John B., Szu, Shousun C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108318/
https://ncbi.nlm.nih.gov/pubmed/9632571
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