Covert Human Immunodeficiency Virus Replication in Dendritic Cells and in DC-SIGN-Expressing Cells Promotes Long-Term Transmission to Lymphocytes

HIV-1 virions are efficiently captured by monocyte-derived immature dendritic cells (iDCs), as well as by cell lines expressing the lectin DC-SIGN. Viral infectivity can be retained for several days, and even enhanced, before transmission to CD4(+) lymphocytes. The role of DC-SIGN in viral retention...

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Main Authors: Nobile, Cinzia, Petit, Caroline, Moris, Arnaud, Skrabal, Katharina, Abastado, Jean-Pierre, Mammano, Fabrizio, Schwartz, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082762/
https://ncbi.nlm.nih.gov/pubmed/15827153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5386-5399.2005
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