Binding and Transfer of Human Immunodeficiency Virus by DC-SIGN(+) Cells in Human Rectal Mucosa

The role of DC-SIGN on human rectal mucosal dendritic cells is unknown. Using highly purified human rectal mucosal DC-SIGN(+) cells and an ultrasensitive real-time reverse transcription-PCR assay to quantify virus binding, we found that HLA-DR(+)/DC-SIGN(+) cells can bind and transfer more virus tha...

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Detalhes bibliográficos
Main Authors: Gurney, Kevin B., Elliott, Julie, Nassanian, Hoorig, Song, Carol, Soilleux, Elizabeth, McGowan, Ian, Anton, Peter A., Lee, Benhur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082722/
https://ncbi.nlm.nih.gov/pubmed/15827191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5762-5773.2005
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