Clostridium difficile Toxin B Induces Apoptosis in Intestinal Cultured Cells

Toxigenic strains of the anaerobic bacterium Clostridium difficile produce at least two large, single-chain protein exotoxins involved in the pathogenesis of antibiotic-associated diarrhea and colitis. Toxin A (CdA) is a cytotoxic enterotoxin, while toxin B (CdB) is a more potent cytotoxin lacking e...

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Bibliographic Details
Main Authors: Fiorentini, Carla, Fabbri, Alessia, Falzano, Loredana, Fattorossi, Andrea, Matarrese, Paola, Rivabene, Roberto, Donelli, Gianfranco
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108253/
https://ncbi.nlm.nih.gov/pubmed/9596731
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