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Differential Effects of Myeloperoxidase-Derived Oxidants on Escherichia coli DNA Replication

The microbicidal myeloperoxidase (MPO)-H(2)O(2)-chloride system strongly inhibits Escherichia coli DNA synthesis. Also, cell envelopes from MPO-treated E. coli cells lose their ability to interact with hemimethylated DNA sequences of oriC, the chromosomal origin of replication, raising the prospect...

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Bibliografiske detaljer
Main Authors: Rosen, Henry, Michel, Bryce R., vanDevanter, Donald R., Hughes, James P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108252/
https://ncbi.nlm.nih.gov/pubmed/9596730
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