Borrelia burgdorferi Escape Mutants That Survive in the Presence of Antiserum to the OspA Vaccine Are Killed When Complement Is Also Present

As an initial attempt to investigate the possible role of outer surface protein A (OspA) escape mutants of Borrelia burgdorferi in decreasing the efficacy of the OspA vaccine, mutants of the HB19 strain of B. burgdorferi sensu stricto were selected in vitro from an uncloned, low-passage-number isola...

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Bibliographic Details
Main Authors: Solé, Mónica, Bantar, Carlos, Indest, Karl, Gu, Yan, Ramamoorthy, Ramesh, Coughlin, Richard, Philipp, Mario T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108236/
https://ncbi.nlm.nih.gov/pubmed/9596714
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