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Neurotoxicity of Clostridium perfringens Epsilon-Toxin for the Rat Hippocampus via the Glutamatergic System

The neurotoxicity of epsilon-toxin, one of the major lethal toxins produced by Clostridium perfringens type B, was studied by histological examination of the rat brain. When the toxin was injected intravenously at a lethal dose (100 ng/kg), neuronal damage was observed in many areas of the brain. In...

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Auteurs principaux: Miyamoto, Osamu, Minami, Junzaburo, Toyoshima, Tetsuhiko, Nakamura, Takehiro, Masada, Tetsuya, Nagao, Seigo, Negi, Tetsuro, Itano, Toshifumi, Okabe, Akinobu
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC108230/
https://ncbi.nlm.nih.gov/pubmed/9596708
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