Streptococcus pneumoniae Type 14 Polysaccharide-Conjugate Vaccines: Length Stabilization of Opsonophagocytic Conformational Polysaccharide Epitopes

A simple and convenient method was developed for the preparation of Streptococcus pneumoniae type 14 polysaccharide (Pn14PS)-tetanus toxoid (TT) conjugate vaccines, using terminally linked Pn14PS fragments of different lengths. Native Pn14PS was simultaneously depolymerized and activated for conjuga...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Laferriere, Craig A., Sood, Ramesh K., de Muys, Jean-Marc, Michon, Francis, Jennings, Harold J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9596700/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.6.2441-2446.1998
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