Protection against Lethal Murine Coccidioidomycosis by a Soluble Vaccine from Spherules

The formaldehyde-killed, whole-spherule vaccine, which is protective against lethal challenge of laboratory animals with Coccidioides immitis, was fractionated. It yielded a soluble, multicomponent, subcellular fraction termed the 27K vaccine. This vaccine, when it was accompanied by adjuvant, prote...

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Autors principals: Zimmermann, C. Roger, Johnson, Suzanne M., Martens, Gregory W., White, Andrew G., Zimmer, Barbara L., Pappagianis, Demosthenes
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC108201/
https://ncbi.nlm.nih.gov/pubmed/9573127
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