Use of a Mycobacterium tuberculosis H37Rv Bacterial Artificial Chromosome Library for Genome Mapping, Sequencing, and Comparative Genomics

The bacterial artificial chromosome (BAC) cloning system is capable of stably propagating large, complex DNA inserts in Escherichia coli. As part of the Mycobacterium tuberculosis H37Rv genome sequencing project, a BAC library was constructed in the pBeloBAC11 vector and used for genome mapping, con...

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Detalhes bibliográficos
Main Authors: Brosch, Roland, Gordon, Stephen V., Billault, Alain, Garnier, Thierry, Eiglmeier, Karin, Soravito, Catherine, Barrell, Bart G., Cole, Stewart T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Molecular Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108185/
https://ncbi.nlm.nih.gov/pubmed/9573111
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