Ambiguous Role of Interleukin-12 in Yersinia enterocolitica Infection in Susceptible and Resistant Mouse Strains

Endogenous interleukin-12 (IL-12) mediates protection against Yersinia enterocolitica in C57BL/6 mice by triggering gamma interferon (IFN-γ) production in NK and CD4(+) T cells. Administration of exogenous IL-12 confers protection against yersiniae in Yersinia-susceptible BALB/c mice but exacerbates...

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Bibliographic Details
Main Authors: Bohn, Erwin, Schmitt, Edgar, Bielfeldt, Claudia, Noll, Annette, Schulte, Ralf, Autenrieth, Ingo B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108184/
https://ncbi.nlm.nih.gov/pubmed/9573110
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