Structural Properties of Group B Streptococcal Type III Polysaccharide Conjugate Vaccines That Influence Immunogenicity and Efficacy

In this study, we tested the hypothesis that the immunogenicity and protective efficacy of polysaccharide-protein conjugate vaccines are influenced by three variables: (i) molecular size of the conjugate, (ii) molecular size of the polysaccharide used for conjugation, and (iii) extent of polysacchar...

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Autores principales: Wessels, Michael R., Paoletti, Lawrence C., Guttormsen, Hilde-Kari, Michon, Francis, D’Ambra, Anello J., Kasper, Dennis L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC108180/
https://ncbi.nlm.nih.gov/pubmed/9573106
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