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Inactivation of the gbpA Gene of Streptococcus mutans Increases Virulence and Promotes In Vivo Accumulation of Recombinations between the Glucosyltransferase B and C Genes

Glucan-binding protein A (GbpA) of Streptococcus mutans has been hypothesized to promote sucrose-dependent adherence and the cohesiveness of plaque and therefore to contribute to caries formation. We have analyzed the adherence properties and virulence of isogenic gbpA mutants relative to those of w...

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Опубликовано в::Infect Immun
Главные авторы: Hazlett, Karsten R. O., Michalek, Suzanne M., Banas, Jeffrey A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1998
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.5.2180-2185.1998
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