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Use of Single Nucleotide Polymorphisms in the plcR Gene for Specific Identification of Bacillus anthracis

A TaqMan-minor groove binding assay designed around a nonsense mutation in the plcR gene was used to genotype Bacillus anthracis, B. cereus, and B. thuringiensis isolates. The assay differentiated B. anthracis from these genetic near-neighbors and determined that the nonsense mutation is ubiquitous...

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Autori principali: Easterday, W. Ryan, Van Ert, Matthew N., Simonson, Tatum S., Wagner, David M., Kenefic, Leo J., Allender, Christopher J., Keim, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1081367/
https://ncbi.nlm.nih.gov/pubmed/15815042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.4.1995-1997.2005
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