Nuclear Translocation of NF-κB in Lipopolysaccharide-Treated Macrophages Fails To Correspond to Endotoxicity: Evidence Suggesting a Requirement for a Gamma Interferon-Like Signal

Elucidation of a signal transduction pathway essential to lipopolysaccharide (LPS)-induced macrophage activation has the capacity to provide new targets for the treatment of septic shock. In this regard, activation of the transcription factor NF-κB is commonly thought to be critical to LPS-stimulate...

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Bibliografiska uppgifter
Huvudupphovsmän: Denlinger, Loren C., Garis, Kristen A., Sommer, Julie A., Guadarrama, Arturo G., Proctor, Richard A., Bertics, Paul J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Host Response and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC108099/
https://ncbi.nlm.nih.gov/pubmed/9529092
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