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M Protein of the Group A Streptococcus Binds to the Seventh Short Consensus Repeat of Human Complement Factor H

Streptococcus pyogenes evades complement by binding the complement-regulatory protein factor H (fH) via the central conserved C-repeat region of M protein. However, the corresponding binding region within fH has not previously been precisely localized. fH is composed of 20 conserved modules called s...

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Autors principals: Blackmore, Timothy K., Fischetti, Vincent A., Sadlon, Tania A., Ward, Helena M., Gordon, David L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC108070/
https://ncbi.nlm.nih.gov/pubmed/9529063
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